The Binding of Isaac: Four Souls Game
The Binding of Isaac: Four Souls Game

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It's All About Sacrifice, Betrayal and Hoarding

Four Souls is a tabletop card game that embodies everything people love about The Binding of Isaac. Two to four players take turns playing loot cards and using items to kill monsters that yield more items, loot and sometimes souls. The first player to end their turn with four souls is the winner!



  • Players can cooperate to fight powerful bosses or sabotage each other
  • Designed by Isaac's creator Edmund McMillen
  • Officially licensed The Binding of Isaac merchandise




  • 340 full-color cards with original artwork designs
  • Also includes 100 custom coins, a pair of dice and a rulebook
  • Expansion packs and other accessories are also available (sold separately)